| Title | Antiproliferative activity of peels, pulps and seeds of 61 fruits |
| Authors | Li, Fang Li, Sha Li, Hua-Bin Deng, Gui-Fang Ling, Wen-Hua Wu, Shan Xu, Xiang-Rong Chen, Feng |
| Affiliation | Sun Yat Sen Univ, Guangdong Prov Key Lab Food Nutr & Hlth, Dept Nutr, Sch Publ Hlth, Guangzhou 510080, Guangdong, Peoples R China. Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Marine Bioresources Sustainable Utilizat, Guangzhou 510301, Guangdong, Peoples R China. Peking Univ, Coll Engn, Inst Food & Bioresource Engn, Beijing 100871, Peoples R China. |
| Keywords | Fruit Peel Pulp Seed Antiproliferative activity Cancer DIETARY PHYTOCHEMICALS CANCER CHEMOPREVENTION ANTICANCER ACTIVITY IN-VITRO ANTIOXIDANT ACTIVITY MILLET GRAINS HUMAN BREAST CELL LINES POLYPHENOLS PHENOLICS |
| Issue Date | 2013 |
| Publisher | journal of functional foods |
| Citation | JOURNAL OF FUNCTIONAL FOODS.2013,5,(3),1298-1309. |
| Abstract | Fruits are wildly consumed and considered to have various health benefits. The aim of this study was to supply new information on the antiproliferative function of selected fruits for nutritionists and the general public. The in vitro antiproliferative activities of the peels, pulps and seeds of 61 fruits on four cancer cell lines, A549 (human lung cancer cells), MCF-7 (human breast cancer cells), HepG2 (human hepatoma cells) and HT-29 (human colon cancer cells) were evaluated by MTT assay. The results revealed that different fruits and different parts of one fruit exhibited different antiproliferative capacities. Nine of the 162 samples from 61 fruits showed remarkable inhibitory effects toward the four cancer cell lines, and all decreased the viability of the cancer cell lines in a dose-dependent manner. The results suggested that some fruits (such as honey peach, salak, orange, and Peru ground cherry) may serve as potential dietary supplement for the prevention and treatment of cancer because of strong antiproliferative activities against the cancer cell lines. (C) 2013 Elsevier Ltd. All rights reserved. |
| URI | http://hdl.handle.net/20.500.11897/222491 |
| ISSN | 1756-4646 |
| DOI | 10.1016/j.jff.2013.04.016 |
| Indexed | SCI(E) |
| Appears in Collections: | 工学院 |
