Title Design, Methodology and Baseline Data of a School-based Cohort Study in Central China: The Anyang Childhood Eye Study
Authors Li, Shi-Ming
Liu, Luo-Ru
Li, Si-Yuan
Ji, Ya-Zhou
Fu, Jing
Wang, Yang
Li, He
Zhu, Bi-Dan
Yang, Zhou
Li, Lei
Chen, Wei
Kang, Meng-Tian
Zhang, Feng-Ju
Zhan, Si-Yan
Wang, Ning-Li
Mitchell, Paul
Affiliation Capital Med Univ, Beijing Tongren Hosp, Beijing Tongren Eye Ctr, Beijing 100730, Peoples R China.
Anyang Eye Hosp, Anyang, Henan Province, Peoples R China.
Harbin Med Univ, Hosp 2, Dept Ophthalmol, Harbin, Peoples R China.
Peking Univ, Sch Publ Hlth, Dept Epidemiol & Hlth Stat, Beijing 100871, Peoples R China.
Univ Sydney, Dept Ophthalmol, Ctr Vis Res, Sydney, NSW 2006, Australia.
Univ Sydney, Westmead Millennium Inst, Sydney, NSW 2006, Australia.
Keywords Children
cohort study
myopia
modifiable risk factors
school-based study
OPTICAL COHERENCE TOMOGRAPHY
PEDIATRIC-REFRACTIVE-ERROR
ULTRA-HIGH-SPEED
VISUAL IMPAIRMENT
HONG-KONG
SINGAPOREAN CHILDREN
MYOPIA PROGRESSION
SOUTHERN CHINA
PERIPHERAL REFRACTION
SHUNYI DISTRICT
Issue Date 2013
Publisher ophthalmic epidemiology
Citation OPHTHALMIC EPIDEMIOLOGY.2013,20,(6),348-359.
Abstract Purpose: To report the design, methods and baseline data of the Anyang Childhood Eye Study (ACES), aiming to determine the prevalence, incidence and risk factors of myopia and other ocular diseases in children in central China. Methods: The ACES was a school-based cohort study conducted in Anyang city. Students have been examined and will be followed-up annually for 3-5 years. Ocular examinations included visual acuity, identification of amblyopia and strabismus, ocular biometry, optical coherence tomography, retinal photography, cycloplegic autorefraction, accommodative response, peripheral refraction, visual perception and so on. A questionnaire survey was performed to collect risk factors for myopia including near work, outdoor activity, parental myopia, birth history, habits of wearing spectacles and reading, living habits, food habits and so on. Results: Of 3112 grade 1 and 2363 grade 7 students eligible for the ACES, 2893 (93.0%) and 2267 (95.9%) participated in the study, with a mean age of 7.1 years (range 5.7-9.3 years) and 12.7 years (range 10.0-15.9 years), and proportions of male to be 57.8% and 50.0%, respectively. The prevalence rates of myopia, high myopia, emmetropia and hyperopia were 3.9%, 0.1%, 72.9% and 23.3% in grade 1, and 67.3%, 2.7%, 31.4% and 1.2% in grade 7, respectively. Similar data were found in the children confined in 6-year-old and 12-year-old ages. Conclusions: The ACES is the first large-scale cohort study in China with baseline response rates over 90%. Continuous documentation of changes and risk factors of refractive errors in these cohorts would provide new insights into myopia control in school-aged children.
URI http://hdl.handle.net/20.500.11897/219335
ISSN 0928-6586
DOI 10.3109/09286586.2013.842596
Indexed SCI(E)
Appears in Collections: 公共卫生学院

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