| Title | Management of recurrent alveolar soft-part sarcoma of the tongue after external beam radiotherapy with iodine-125 seed brachytherapy |
| Authors | Meng, Na Zhang, Xiaomeng Liao, Anyan Tian, Suqing Ran, Weiqiang Gao, Yang Wang, Jun Jie |
| Affiliation | Peking Univ Third Hosp, Dept Radiat Oncol, Beijing 100191, Peoples R China. Harvard Univ, Massachusetts Gen Hosp, Sch Med, Ctr Adv Med Imaging Sci, Boston, MA 02115 USA. Peking Univ Third Hosp, Dept Ultrasound, Beijing 100191, Peoples R China. |
| Keywords | I-125 seed brachytherapy ultrasound guidance alveolar soft-part sarcoma outcome IMPLANTATION CHILDREN HEAD NECK |
| Issue Date | 2014 |
| Publisher | head and neck journal for the sciences and specialties of the head and neck |
| Citation | HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK.2014,36,(12),E125-E128. |
| Abstract | BackgroundAlveolar soft part sarcoma (ASPS) is a rare type of soft tissue sarcoma. The infrequency of ASPS is such that it accounts for <1% of all soft tissue sarcomas and <0.1% of sarcomas concerning the head and neck, primarily those involving the orbit (48%) and tongue (25%). Traditional chemotherapy or radiotherapy of ASPS is often associated with poor outcome, even after comprehensive interventions. Methods and ResultsWe performed iodine-125 (I-125) seed brachytherapy under ultrasound guidance through a submandibular puncture in a 4-year-old boy with recurrent ASPS of the tongue. The prescription dose was 120 Gy; therefore, 35 I-125 seeds were implanted with 0.77 mCi per seed, the total amount of activity being 26.95 mCi. CT scans confirmed a complete response after the treatment. ConclusionOur patient now has a recurrent-free survival of >30 months, an amount of time longer than the median rate described in the literature. (c) 2014 Wiley Periodicals, Inc. Head Neck 36: E125-E128, 2014 |
| URI | http://hdl.handle.net/20.500.11897/189420 |
| ISSN | 1043-3074 |
| DOI | 10.1002/hed.23648 |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 第三医院 |
