| Title | Implementation of gastric cancer screening - The global experience |
| Authors | Leja, Marcis You, Weicheng Camargo, M. Constanza Saito, Hiroshi |
| Affiliation | Univ Latvia, Fac Med, LV-1006 Riga, Latvia. Peking Univ Canc Hosp & Inst, Dept Canc Epidemiol, Key Lab Carcinogenesis & Translat Res, Minist Educ, Beijing 100142, Peoples R China. NCI, Div Canc Epidemiol & Genet, Rockville, MD USA. Natl Canc Ctr, Res Ctr Canc Prevent & Detect, Canc Screening Assessment & Management Div, Tokyo 1040045, Japan. Univ Latvia, Fac Med, 6 Linezera Iela, LV-1006 Riga, Latvia. |
| Keywords | Biomarkers Gastric cancer Helicobacter pylori Precancerous lesions Screening HELICOBACTER-PYLORI ERADICATION SERUM PEPSINOGEN STOMACH-CANCER HIGH-RISK COST-EFFECTIVENESS FOLLOW-UP PRECANCEROUS LESIONS MULTIPLEX SEROLOGY GENE POLYMORPHISMS CHINESE POPULATION |
| Issue Date | 2014 |
| Citation | BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY.2014,28,(6),1093-1106. |
| Abstract | Gastric cancer (GC) is still an important global healthcare problem, and in absolute figures it is going to remain at the present level in foreseeable future. In general, survival' of patients with GC is poor mainly due to advanced-stage diagnosis. Early-stage GC can be cured by endoscopic resection or less invasive surgical treatment. Unfortunately, there is no appropriate screening strategy available for global application. This article provides a description of established national and regional GC screening programs and the screening modalities used. This review also summarizes current approaches to develop cancer-screening biomarkers. Although candidates with initial promising results have been suggested, moving discovery into clinical practice is still a major challenge. Well-designed biomarker studies, with systematic validation steps, are needed to decrease the burden of this fatal disease. (C) 2014 Elsevier Ltd. All rights reserved. |
| URI | http://hdl.handle.net/20.500.11897/188494 |
| ISSN | 1521-6918 |
| DOI | 10.1016/j.bpg.2014.09.005 |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 北京肿瘤医院 |
