| Title | "Focal thyroid inferno" on color Doppler ultrasonography: A specific feature of focal Hashimoto's thyroiditis |
| Authors | Fu, Xianshui Guo, Limei Zhang, Huabin Ran, Weiqiang Fu, Peng Li, Zhiqiang Chen, Wen Jiang, Ling Wang, Jinrui Jia, Jianwen |
| Affiliation | Peking Univ, Hosp 3, Dept Ultrasound, Beijing 100191, Peoples R China. Peking Univ, Hosp 3, Dept Pathol, Beijing 100191, Peoples R China. Peking Univ, Hosp 3, Dept Ultrasound, 49 Huayuanbeilu Rd, Beijing 100191, Peoples R China. |
| Keywords | Hashimoto's thyroiditis Doppler ultrasonography Thyroid nodules GRAVES-DISEASE NODULES MALIGNANCY BENIGN US ULTRASOUND VASCULARITY SONOGRAPHY RISK |
| Issue Date | 2012 |
| Publisher | european journal of radiology |
| Citation | EUROPEAN JOURNAL OF RADIOLOGY.2012,81,(11),3319-3325. |
| Abstract | Purpose: To evaluate color-Doppler features predictive of focal Hashimoto's thyroiditis. Materials and methods: A total of 521 patients with 561 thyroid nodules that underwent surgeries or gun biopsies were included in this study. These nodules were divided into three groups: focal Hashimoto's thyroiditis (104 nodules in 101 patients), benignity other than focal Hashimoto's thyroiditis (73 nodules in 70 patients), and malignancy (358 nodules in 350 patients). On color Doppler sonography, four vascularity types were determined as: hypovascularity, marked internal flow, marked peripheral flow and focal thyroid inferno. The chi(2) test was performed to seek the potential vascularity type with the predictive ability of certain thyroid pathology. Furthermore, the gray-scale features of each nodule were also studied. Results: The vascularity type I (hypovascularity) was more often seen in focal Hashimoto's thyroiditis than other benignity and malignancy (46% vs. 20.5% and 19%). While the type II (marked internal flow) showed the opposite tendency (26.9% [focal Hashimoto's thyroiditis] vs. 45.2% [other benignity] and 52.8% [malignancy]). However, type III (marked peripheral flow) was unable to predict any thyroid pathology. Importantly, type IV (focal thyroid inferno) was exclusive to focal Hashimoto's thyroiditis. All 8 type IV nodules appeared to be solid, hypoechoic, and well-defined. Using "focal thyroid inferno" as an indicator of FHT, the diagnostic sensitivity and specificity were 7.7% and 100% respectively. Conclusions: The vascularity type of "focal thyroid inferno" is specific for focal Hashimoto thyroiditis. Recognition of this particular feature may avoid unnecessary interventional procedures for some solid hypoechoic thyroid nodules suspicious of malignancy. (C) 2012 Elsevier Ireland Ltd. All rights reserved. |
| URI | http://hdl.handle.net/20.500.11897/161462 |
| ISSN | 0720-048X |
| DOI | 10.1016/j.ejrad.2012.04.033 |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 第三医院 |
