Title | Dietary and inhalation exposure to polycyclic aromatic hydrocarbons and urinary excretion of monohydroxy metabolites - A controlled case study in Beijing, China |
Authors | Zhang, Yanyan Ding, Junnan Shen, Guofeng Zhong, Junjun Wang, Chen Wei, Siye Chen, Chaoqi Chen, Yuanchen Lu, Yan Shen, Huizhong Li, Wei Huang, Ye Chen, Han Su, Shu Lin, Nan Wang, Long Liu, Wenxin Tao, Shu |
Affiliation | Peking Univ, Coll Urban & Environm Sci, Lab Earth Surface Proc, Beijing 100871, Peoples R China. |
Keywords | Polycyclic aromatic hydrocarbons Dietary exposure Urinary excretion Biomarkers LUNG-CANCER RISK OCCUPATIONAL-EXPOSURE DIFFERENT INDUSTRIES MASS-SPECTROMETRY TRAFFIC POLICE US POPULATION 1-HYDROXYPYRENE PAHS WORKERS PYRENE |
Issue Date | 2014 |
Publisher | environmental pollution |
Citation | ENVIRONMENTAL POLLUTION.2014,184,(,SI),515-522. |
Abstract | Daily dietary and inhalation exposures to 16 parent polycyclic aromatic hydrocarbons (PAHs) and urinary excretion of 13 monohydroxy metabolites (OHPAHs) were monitored for 12 non-smoking university students in Beijing, China, during a controlled feeding experiment. The relationship between the urinary excretion of OHPAHs and the uptake of PAHs was investigated. The results suggest severe exposure of the subjects to PAHs via both dietary and inhalation pathways. Large increase of most urinary OHPAHs occurred after the ingestion of lamb kabob. Higher concentrations of OHPAHs were observed for female subjects, with the intakes of parent PAHs lower than those by males, likely due to the gender differences in metabolism. It appears that besides 1-PYR, metabolites of PHE could also be used as biomarkers to indicate the short-term dietary exposure to PAHs and urinary 3-BaA may serve as the biomarker for inhalation intake of high molecular weight PAHs. (C) 2013 Elsevier Ltd. All rights reserved. |
URI | http://hdl.handle.net/20.500.11897/160565 |
ISSN | 0269-7491 |
DOI | 10.1016/j.envpol.2013.10.005 |
Indexed | SCI(E) EI PubMed |
Appears in Collections: | 城市与环境学院 地表过程分析与模拟教育部重点实验室 |