| Title | Diastereoselective Povarov-Like Reaction Involving O-Pivaloylated D-Galactosylimine |
| Authors | Wang, Gang Li, Boyu Lou, Qinghua Li, Zhongjun Meng, Xiangbao |
| Affiliation | Peking Univ, State Key Lab Nat & Biomimet Drugs, Dept Biol Chem, Sch Pharmaceut Sci, Beijing 100191, Peoples R China. |
| Keywords | asymmetric synthesis carbohydrate auxiliary multicomponent reactions Povarov-like reactions scandium triflate [Sc(OTf)(3)] BETA-AMINO ACIDS STEREOSELECTIVE STRECKER SYNTHESIS DIELS-ALDER REACTIONS N-ARYL IMINES CHIRAL TEMPLATES MULTICOMPONENT REACTIONS CARBOHYDRATE TEMPLATES ASYMMETRIC-SYNTHESIS UGI-SYNTHESIS DECAHYDROQUINOLINE ALKALOIDS |
| Issue Date | 2013 |
| Publisher | 高级合成与催化 |
| Citation | ADVANCED SYNTHESIS & CATALYSIS.2013,355,(2-3),303-307. |
| Abstract | A diastereoselective Povarov-like reaction using O-pivaloylated -D-galactosylamine as the chiral auxiliary is described. The three-component reaction of chiral aldimines, cyclic enol ethers and nucleophiles afforded the desired products in good yields and high content of the main isomer. This procedure provides an efficient method to obtain multifunctional molecules carrying three contiguous chiral centers in high stereoselectivity. |
| URI | http://hdl.handle.net/20.500.11897/157086 |
| ISSN | 1615-4150 |
| DOI | 10.1002/adsc.201200761 |
| Indexed | SCI(E) |
| Appears in Collections: | 药学院 天然药物与仿生药物国家重点实验室 |
