| Title | Antioxidant flavonoids from Epimedium wushanense |
| Authors | Li, Hui-fang Guan, Xiang-yu Yang, Wen-zhi Liu, Ke-di Ye, Min Sun, Chao Lu, Shuang Guo, De-an |
| Affiliation | Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China. Guizhou Acad Sci, Inst Biol, Guiyang, Peoples R China. Guiyang Med Univ Affiliated Hosp, Guiyang, Peoples R China. |
| Keywords | Epimedium wushanense Berberidaceae Flavonoid DPPH Antioxidant MASS-SPECTROMETRY GLYCOSIDES SAGITTATUM ROOTS |
| Issue Date | 2012 |
| Publisher | fitoterapia |
| Citation | FITOTERAPIA.2012,83,(1),44-48. |
| Abstract | Two new flavonoids, wushanicaritin (1) and wushankaempferol (2), along with 24 known flavonoids were isolated from the whole herb of Epimedium wushanense T.S. Ying (Berberidaceae). On the basis of NMR and ESI-MS spectroscopic analysis, structures of compounds 1 and 2 were elucidated as 8-gamma-hydroxy-y-gamma,gamma-dimethylpropyl-3,5,7-trihydroxy-4'. methoxyflavone and kaempferol 3-O-alpha-L-[2,3-di-O-beta-D-(6-E-p-coumaroyl) glucopyranosyl]-rhamnopyranosyl-7-O-alpha-L-rhamnopyranoside, respectively. DPPH radical scavenging activity tests indicated that 1 (IC50 35.3 mu M) exhibited antioxidant activity comparable to Vitamin C (IC50 32.0 mu M). while 2 (IC50 443.7 mu M) showed weak activity. (C) 2011 Elsevier B.V. All rights reserved. |
| URI | http://hdl.handle.net/20.500.11897/156676 |
| ISSN | 0367-326X |
| DOI | 10.1016/j.fitote.2011.09.010 |
| Indexed | SCI(E) PubMed |
| Appears in Collections: | 药学院 天然药物与仿生药物国家重点实验室 |
