| Title | A Bioorthogonal Raman Reporter Strategy for SERS Detection of Glycans on Live Cells |
| Authors | Lin, Liang Tian, Xiangdong Hong, Senlian Dai, Peng You, Qiancheng Wang, Ruyi Feng, Lianshun Xie, Can Tian, Zhong-Qun Chen, Xing |
| Affiliation | Peking Univ, Dept Biol Chem, Coll Chem & Mol Engn, Synthet & Funct Biomol Ctr, Beijing 100871, Peoples R China. Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China. Peking Univ, Sch Life Sci, Beijing 100871, Peoples R China. Xiamen Univ, Coll Chem & Chem Engn, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China. |
| Keywords | bioorthogonality cells glycans Raman spectroscopy surface science SCATTERING MICROSCOPY SIALIC-ACID CYCLOADDITION SPECTROSCOPY MOLECULES |
| Issue Date | 2013 |
| Publisher | angewandte chemie international edition |
| Citation | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.2013,52,(28),7266-7271. |
| Abstract | Direct detection of glycans on live cells using surface-enhanced Raman scattering (SERS) has been shown. A bioorthogonal Raman reporter was directly installed onto the monosaccharide analogs. Once metabolically incorporated into cell surface glycans, the Raman reporter was detected using SERS (see picture). Copyright ? 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
| URI | http://hdl.handle.net/20.500.11897/149755 |
| ISSN | 1433-7851 |
| DOI | 10.1002/anie.201301387 |
| Indexed | SCI(E) EI PubMed |
| Appears in Collections: | å å¦ä¸ å å å·¥ç¨ å¦é ¢ 生命科学学院 |
